1H-Pyrazolo[4,3-b]pyridine - Names and Identifiers
1H-Pyrazolo[4,3-b]pyridine - Physico-chemical Properties
Molecular Formula | C6H5N3
|
Molar Mass | 119.12 |
Density | 1.348±0.06 g/cm3(Predicted) |
Boling Point | 294.5±13.0 °C(Predicted) |
Flash Point | 145.716°C |
Vapor Presure | 0.003mmHg at 25°C |
pKa | 10.94±0.30(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.715 |
MDL | MFCD08234560 |
1H-Pyrazolo[4,3-b]pyridine - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | 22 - Harmful if swallowed
|
1H-Pyrazolo[4,3-b]pyridine - Introduction
1H-Pyrazolo[4,3-b]pyridine(1H-Pyrazolo[4,3-b]pyridine) is an organic compound with the chemical formula C9H6N2. The following is a description of the nature, use, preparation and safety information of 1H-Pyrazolo[4,3-b]pyridine:
Nature:
- 1H-Pyrazolo[4,3-b]pyridine is a white to pale yellow solid with a melting point of about 160-165°C.
-It is soluble in common organic solvents such as dimethyl sulfoxide, dichloromethane and dimethylformamide, but the solubility is low.
- 1H-Pyrazolo[4,3-b]pyridine has the characteristics of a typical aromatic compound and can emit a special aroma.
Use:
- 1H-Pyrazolo[4,3-b]pyridine is an important organic synthesis intermediate, which can be used to synthesize many biologically active compounds, such as drugs, pesticides and dyes.
-It can also be used as a building block for organic optoelectronic materials, such as organic photovoltaic devices and organic electroluminescent diodes (OLED).
Method:
- 1H-Pyrazolo[4,3-b]pyridine can be prepared by a variety of synthetic methods, among which the more common method is the reaction using pyridine and hydrazine as raw materials.
-using acetylacetone as solvent, heating reaction generates intermediate 1h-pyrazolopyridin-3-one (1H-pyrazolo[4,3-b]pyridin-3-one), after further chemical conversion reaction, the target product 1H-Pyrazolo[4,3-b]pyridine was obtained.
Safety Information:
- 1H-Pyrazolo[4,3-b]pyridine has limited toxicity and safety data, so appropriate safety measures should be taken when using and storing.
-When handling, avoid direct contact with skin, eyes and respiratory tract to avoid irritation.
-When storing, it is recommended to keep the compound in a dry, cool, dark place, and avoid contact with oxygen, air and water.
-Use in accordance with chemical safety practices and wear appropriate protective equipment such as gloves, laboratory glasses and masks.
Last Update:2024-04-09 20:49:11